Very very long period of time, ozone is toxic to reef habitat so use it carefully. I think you use it for skimmer. Can I ask what kind of skimmer are you plan to use, because I don't know any all-in-one skimmer capable to work with ozone?
If I don't use a skimmer, I was thinking about just running the ozone in one of the back chambers to help keep the water looking crystal clear. I just don't want the integrity or the clarity of acrylic of the acrylic to be affected by using the ozone in one of the back chambers.