I have run Ozone 24/7 on my system since startup. I run a reactor and carbon on exported water and air. I have a fish room in garage, so was not to worried about health issues. I change Carbon every 6 months and the water looks like the fish are floating in air. I think if implemented correctly can be a benefit, as seen in most public aquariums. With that said Carbon does almost the same thing the difference is the Ozone is static and keeps everything more stable. Carbon if you looked at on a graph would spike when you first put in and then drop off until it is changed. Ozone once dialed in is constant.
It does add a bunch of equipment and expense, I change Ozone generators every couple years and have invested in a auto air dryer.
Here is a drawing of what I have.
http://www.marinetechnical.com/page9.html
My Ozitech Black Ozone generator is dialed into setting 6 and my ORP stays pretty constant below the rev limiter close to 400.
I bought the reactor from MTC most everything else I have from BRS.
I once had a line on generator plastic break off and my fish room smelled like Triton had been throwing down some bolts, but I am still alive and it aired out quickly.
My 90 quarantine has much cleaner parameters than my 400, but I do run a very heavy fish load and my SPS seems very happy at the moment.
Yes SPS is sometimes tricky and it is a love hate relationship. Today I am loving!