OK, wanna here my experience? The only thing that worked for me is Kordon Ick Attack it is 100% Natural, & Reef safe, and it works, AND you can get it at petsmart, BUT you have to over dose! I dose three times a day, and it's affordable! NOW REMEMBER THIS ONLY WORKS IF YOU CATCH IT AS SOON AS YOU SEE IT!!! If fish are breathing hard 99% of the time it's death, sorry